Researchers / Publications
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Publications

2012-Present | 2010-2011 | 2005-2010 | 2000-2005 | 1998-2000


2000-2005


Aizenstein HJ, Clark KA, Butters MA, Cochran J, Stenger VA, Meltzer CC, Reynolds CF, Carter CS. The BOLD Hemodynamic Response in Healthy Aging. Journal of Cognitive Neuroscience. In press, 2004.

Aizenstein HJ, Nebes RD, Meltzer CC, Fukui MB, Williams RL, Saxton J, Houck PR, Carter CS, Reynolds III CF, DeKosky ST: The relation of White Matter Hyperintensities to implicit learning in healthy older adults. Int J Geriatr Psychiatry 17:664-669, 2002.

Aizenstein HJ, MacDonald AW, Stenger VA, Nebes RD, Larson JK, Ursu S, Carter CS: Complementary Category Learning Systems Identified Using Event-Related Functional MRI. J Cognitive Neuroscience. 12(6):977-987, 2000.

Bacanu SA, Devlin B, Chowdari KV, DeKosky ST, Nimgaonkar VL, Sweet RA: Linkage analysis of Alzheimer disease with psychosis. Neurology, 59:118-120, 2002.

Bacskai BJ, Klunk WE, Mathis CA, Hyman BT. Imaging amyloid-beta deposits in vivo. J. Cerebral Blood Flow and Metabolism 2002; 22: 1035-1041.

Bacskai BJ, Hickey GA, Skoch J, Kajdasz ST, Wang Y, Huang G-F, Mathis CA, Klunk WE, and Hyman BT. Four-dimensional multiphoton imaging of brain entry, amyloid binding, and clearance of an amyloid-ß ligand in transgenic mice. PNAS 100:12462-12467, 2003.

Baird A, Podell K, Lovell M, Bell McGinty S. Complex real-world functioning and neuropsychological test performance in older adults. The Clinical Neuropsychologist 2001;15(3):369-379.

Basu A, Krady JK, O'Malley M, Styren SD, DeKosky ST, Levison SW: The Type 1 Interleukin-1 Receptor Is Essential for the Efficient Activation of Microglia and the Induction of Multiple Proinflammatory Mediators in Response to Brain Injury. The Journal of Neuroscience 22(14):6071-6082, 2002.

Bell-McGinty SB, Butters MA, Meltzer CC, Greer PJ, Reynolds CF, Becker JT. Brain morphometric abnormalities in late-life depression: long-term neurobiological effects of illness duration. American Journal of Psychiatry 2002;159:1424-1427.

Bell-McGinty S, Lopez OL, Meltzer CC, Scanlon JM, Whyte EM, DeKosky ST, and Becker, JT: Differential Cortical Atrophy in Subgroups of Mild Cognitive Impairment. Archives of Neurology, 2004 [In Press].

Belle SH, Mendelsohn AB, Seaberg EC, Ratcliff G: A Brief Cognitive Screening Battery for Dementia in the Community. Neuroepidemiology 19:43-50, 2000.

Berthier M, Kulisevsky J, Girdnell A, Lopez OL: Obsessive-Compulsive Disorder and Traumatic Brain Injury: Behavioral, Cognitive, and Neuroimaging Findings. Neuropsychiatry, Neuropsychology and Behavioral Neurology 14:23-31, 2001.

Bhojak TJ, DeKosky ST, Ganguli M, Kamboh MI: Genetic polymorphisms in the cathespin D and interleukin-6 genes and the risk of Alzheimer's disease. Neuroscience Letters 288:21-24, 2000.

Bhojak TJ, DeKosky ST, Ganguli M, Kamboh MI: Genetic polymorphism in the cathepsin G gene and the risk of Alzheimer's disease. Neuroscience Letters 309:138-140, 2001.

Boada M, Cejudo JC, Tarraga LI, Lopez OL, Kaufer DI: Neuropsychiatric Inventory Questionnaire (NPI-Q): Spanish validation of the brief form of the neuropsychiatric inventory. Revista de Neurologia (Spain) 17:317-323, 2002.

Bohnen NI, Kaufer DI, Ivanco LS, Lopresti B, Koeppe RA, Davis JG, Mathis CA, Moore RY, DeKosky ST: Cortical Cholinergic Function is More Severely Affected in Parkinsonian Dementia Than in Alzheimer's Disease. Arch. Neruol 60:1745-1748, 2003.

Bohnen N, Kaufer D, Hendrickson R, Ivanco L, Moore R, DeKosky S. Effects of Donepezil on Motor Function in Patients with Alzheimer's Disease. J Clin Psychopharmacology. In Press, 2004.

Burmeister LA, Ganguli M, Dodge HH, Toczek T, DeKosky ST, Nebes RD: Hypothyroidism and Cognition: Preliminary Evidence for a Specific Defect in Memory. Thyroid 11(12):1177-1185, 2001.

Butters MA, Becker JT, Nebes RD, Zmuda MD, Mulsant BH, Pollock BG, Reynolds CF: Changes in Cognitive Functioning Following Treatment of Late-Life Depression. Am J of Psychiatry 157(12): 1949-1954, 2000.

Butters MA, Sweet RA, Mulsant BH, Kamboh MI, Pollock BG, Begley AE, Reynolds CD, DeKosky ST: APOE is associated with age-of-onset, but not cognitive functioning, in late-life depression. International J of Geriatric Psychiatry. In Press, 2004.

Butters MA, Whyte E, Nebes RD, Begley AE, Drew MA, Mulsant BH, Zmuda MD, Bhalla R, Meltzer CC, Pollock BG, Reynolds CF, Becker JT: Nature and Determinants of Neuropsychological Functioning in Late-Life Depression. Archives of General Psychiatry. In Press, 2004.

Carter TL, Rissman RA, Mishizen-Eberz AJ, Wolfe BB, Hamilton RL, Armstrong DM: Biochemical Study of AMPA Receptor Subunits in the Hippocampus of Alzheimer's Disease Patients. Experimental Neurology, in press, 2004.

Chandra V, Pandav R, Dodge HH, Johnston JM, Belle SH, DeKosky ST, Ganguli M: Incidence of Alzheimer's disease in a rural community in India: The Indo-US Study. Neurology 57:985-989, 2001.

Chen P, Ratcliff G, Belle SH, Cauley JA, DeKosky ST, Ganguli M: Cognitive Tests That Best Discriminate Between Presymptomatic AD and Those Who Remain Nondemented. Neurology 55:1847-1853, 2000.

Chen P, DeKosky ST, Ganguli M: Cognitive tests that best discriminate between presymptomatic AD and those who remain nondemented. Letter, Neurology 57:163-164, 2001.

Chen P, Ratcliff G, Belle SH, Cauley JA, DeKosky ST, Ganguli M: Patterns of Cognitive Decline in Presymptomatic Alzheimer Disease: A Prospective Community Study. Archives of General Psychiatry 58:853-858, 2001.

Coffey CE, Ratcliff G, Saxton J, Bryan RN, Fried LP, Lucke JF: Cognitive Correlates of Human Brain Aging: A Quantitative Magnetic Resonance Imaging Investigation. J of Neuropsychiatry and Clinical Neurosciences 13(4):471-485, 2001.

Cook SE, Nebes RD, Halligan EM, Burmeister LA, Saxton JA, Ganguli M, Fuku MB, Meltzer CC, Williams RL, and DeKosky ST: Memory Impairment in Elderly Individuals With a Mildly Elevated Serum TSH: The Role of Processing Resources, Depression and Cerebrovascular Disease. Aging, Neuropsychology and Cognition 2002, 9, 175-183.

Cook SE, Miyahara S, Bacanu SA, Perez-Madrinan G, Lopez OL, Kaufer DI, Nimgoankar VL, Wisniewski S, DeKosky ST, Sweet RA: Psychotic Symptoms in Alzheimer's Disease: Evidence for Subtypes. Am J Geriatr Psychiatry 11(4):406-413, 2003.

Cronin-Stubbs D, DeKosky ST, Morris JC, Phelps CH, Evans DA: Promoting interactions with basic scientists and clinicians: The NIA Alzheimer's Disease Data Coordinating Center. Statistics in Medicine 19:1435-1461, 2000.

DeKosky ST and Orgogozo J-M: Alzheimer's Disease: Diagnosis, Costs, and Dimensions of Treatment. Alzheimer Disease and Association Disorders 15, Supplement 1, S3-S7, 2001.

DeKosky ST, Ikonomovic MD, Styren SD, Beckett L, Wisniewski S, Bennett DA, Cochran EJ, Kordower JH, Mufson EJ: Upregulation of Choline Acetyltransferase Activity in Hippocampus and Frontal Cortex of Elderly Subjects with Mild Cognitive Impairment. Annals of Neurology 51:145- 155, 2002.

DeKosky ST, Ikonomovic MD, Wang X, Farlow M, Wisniewski S, Lopez OL, Becker JT, Saxton J, Klunk WE, Sweet R, Kaufer DI, Kamboh MI: Plasma and Cerebrospinal Fluid 1- Antichymotrypsin Levels in Alzheimer's Disease: Correlation with Cognitive Impairment. Annals of Neurology 53:81-90, 2003.

DeKosky ST: Similar Enzymes, Different Mechanisms. Archives of Neurology 60:632-633, 2003.

DeKosky ST: Pathology and Pathways of Alzheimer's Disease With an Update on New Developments in Treatment. Journal of the American Geriatrics Society 51:S314-S320,2003.

DeKosky S: Early Intervention is Key to Successful Management of Alzheimer Disease. Alzheimer Disease and Associated Disorders 17:S99-S104, 2003.

DeKosky ST, and Marek K: Looking Backward to Move Forward: Early Detection of Neurodegenerative Disorders. Science 302:830-834, 2003.

Desai P, DeKosky ST, Kamboh MI: Genetic variation in the cholesterol 24-hydroxylase (CYP46) gene and the risk of Alzheimer's disease. Neuroscience Letters 328:9-12, 2002.

Desai PP, Hendrie HC, Evans RM, Murrell JR, DeKosky ST, Kamboh MI: Genetic Variation in Apolipoprotein D Affects the Risk of Alzheimer's Disease in African-Americans. Am J of Medical Genetics Part B (Neuropsychiatric Genetics) 116B:98-101, 2003.

Dodge HH, Shen C, Pandav R, DeKosky ST, and Ganguli M: Functional Transitions and Active Life Expectancy associated with Alzheimer's Disease. Archives of Neurology 60: 253-259, 2003.

Doody RS, Stevens JC, Beck C, Dubinsky RM, Kaye JA, Gwyther L, Mohs RC, Thal LJ, Whitehouse PJ, DeKosky ST, Cummings JC: Practice parameter: Management of dementia (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 56:1154-1166, 2001.

Drevets WC, Gautier C, Price JC, Kupfer DJ, Kinahan PE, Grace AA, Price JL, Mathis CA. Amphetamine-induced dopamine release in human ventral striatum correlates with euphoria. Biological Psychiatry 2001; 49:81-96.

Fabian TJ, Dew MA, Pollock BG, Reynolds CF, Mulsant BH, Butters MA, Zmuda MD, Linares AM, Trottini M, Kroboth PD: Endogenous Concentrations of DHEA and DHEA-S Decrease with Remission of Depression in Older Adults. Biological Psychiatry 50(10):767-774, 2001.

Ganguli M, Chandra V, Kamboh MI, Johnston JM, Dodge HH, Thema BK, Juyal RC, Pandav R, Belle SH, DeKosky ST: Apolipoprotein E Polymorphism and Alzheimer Disease. Arch Neurol 57:824-830, 2000.

Ganguli M, Dodge HH, Chen P, Belle S, DeKosky ST: Ten-year incidence of dementia in a rural elderly US community population. Neurology 54:1109-1116, 2000.

Garand L, Dew MA, Eazor LR, DeKosky ST, Reynolds CF III: Caregiving burden and psychiatric morbidity in spouses of persons with mild cognitive impairment. Int J Geriatr Psych 20:512-522, 2005.

Garand L, Dew MA, Urda B, Hagerty Lingler J, DeKosky ST, and Reynolds C.F. III: Marital quality in the context of mild cognitive impairment. Western Journal of Nursing Research. 29(8), 976-992. PMID: 17984481

Greer PJ, Villemagne VL, Ruszkiewicz J, Graves AK, Meltzer CC, Mathis CA, Price JC. MR atlas of the baboon brain for functional neuroimaging. Brain Research Bulletin 2002;58(4):429-438.

Halks-Miller M, Schroeder ML, Haroutunian V, Moenning U, Rossi M, Achim C, Purohit D, Mahmoudi M, Horuk R: CCR1 Is an Early and Specific Marker of Alzheimer's Disease. Ann Neurol 54:638-646, 2003.

Hamilton RL: Lewy Bodies in Alzheimer's Disease: A Neuropathological Review of 145 Cases Using -Synuclein Immunohistochemistry. Brain Pathology 10:378-384, 2000.

Hamilton RL: The Other Dementias: The Neuropathology of the Non-Alzheimer's Disease Dementias. Rev Neurol 37:130-139, 2003 (Spanish).

Hope C, Mettenburg J, Gonias SL, DeKosky ST, Kamboh MI, Chu CT: Functional analysis of plasma ?2-macroglobulin from Alzheimer's disease patients with the A2M intronic deletion. Neurobiology of Disease 14:504-512, 2003.

Ikonomovic MD, Mufson EJ, Wuu J, Cochran EJ, Bennett DA and DeKosky ST: Cholinergic plasticity in hippocampus of individuals with mild cognitive impairment: Correlation with Alzheimer's neuropathology. J Alz Disease 5:39-48, 2003.

Jordan-Sciutto KL, Caltagarone DJ, Hall DJ, Bowser R: Fetal Alz-50 Clone 1 (FAC1) Protein Interacts with the Myc-Associated Zinc Finger Protein (ZF87/MAZ) and Alters Its Transcriptional Activity. Biochemistry 39(12):3206-3215, 2000.

Jordan-Scuitto K, Rhodes J, Bowser R: Altered subcellular distribution of transcriptional regulators in response to A peptide and during Alzheimer's disease. Mechanisms of Aging and Development 123:11-20, 2001.

Jordan-Scuitoo KL, Malaiyandi LM and Bowser: Altered distribution of Cell Cylce Transcriptional Regulators During Alzheimer's Disease. J. Neuropathol Exp. Neurol 61:358-367, 2002.

Kaufer DI, Cummings JL, Ketchel P, Smith V, MacMillan A, Shelley T, Lopez OL, DeKosky ST: Validation of the NPI-Q, a brief Clinical Form of the Neuropsychiatric Inventory. Journal of Neuropsychiatry and Clinical Neuroscience 12(2): 233-239, 2000.

Kaufer DI: Cholinesterase-inhibitor Therapy for Dementia: Novel Clinical Substrates and Mechanisms for Treatment Response. CNS Spectrums 7(10):742-750, 2002 /

Kaufer DI: Pharmacologic Therapy of Dementia with Lewy Bodies. J Geriatr Psychiatry Neurol 15:224-232, 2002.

Kaufer DI. Dementia and Lewy Bodies. Rev Neurol 37:127-30, 1003. (Spanish)

Kaufer DI. Pharmacologic treatment expectations in the management of dementia with Lewy bodies. Dement Geriatr Cogn Disord 17(1):32-39, 2004.

Kerr ME, Kamboh MI, Yookyung K, Kraus MF, Puccio AM, DeKosky ST, and Marion DW: Relationship between apoE4 allele and excitatory amino acid levels after traumatic brain injury. Critical Care Medicine 31:2371-2379, 2003.

Klunk WE, Wang Y, Huang G, Debnath ML, Holt DP, Mathis C: Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain. Life Sciences 69:1471-1484, 2001.

Klunk WE, Bacskai BJ, Mathis CA, Kajdasz ST, McLellan ME, Frosch MP, Debnath ML, Holt DP, Wang Y, Hyman BT: Imaging A Plaques in Living Transgenic Mice with Multiphoton Microscopy and Methoxy-X04, a Systemically Administered Congo Red Derivative. J of Neuropath and Exper Neurology 61(9):797-805, 2002.

Klunk WE. Blood and CSF biomarkers for AD revisited: what's new, what's good and is this where we should be looking? Neurobiol. Aging 23:517-519, 2002.

Klunk WE, Wang Y, Huang G, Debnath ML, Holt DP, Shao L, Hamilton RL, Ikonomovic MD, DeKosky ST, Mathis CA. The Binding of 2-(4'-Methylaminophenyl) Benzothiazole to Postmortem Brain Homogenates Is Dominated by the Amyloid Component. J Neurosci. 23:2086-2092, 2003.

Klunk WE, Engler H, Nordberg A, Wang Y, Blomqvist G, Holt DP, Bergström M, Savitcheva I, Huang G, Estrada S, Ausen B, Debnath ML, Barletta J, Price J, Sandell J, Lopresti BJ, Wall A, Koivisto P, Antoni G, Mathis CA, Langström B: Imaging Brain Amyloid in Alzheimer's Disease Using the Novel Positron Emission Tomography Tracer, Pittsburgh Compound-B. Ann Neurol 55:000-000, 2004 In Press.

Knopman DS, DeKosky ST, Cummings JL, Chui H, Corey-Bloom J, Relkin N, Small GW, Miller B, Stevens JC: Practice parameter: Diagnosis of dementia (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 56:1143-1153, 2001.

Koldamova RP, Lefterov IM, Lefterova MI, Lazo JS: Apolipoprotein A-1 Directly Interacts with Amyloid Precursor Protein and Inhibits A Aggregation and Toxicity. Biochemistry 40(12):3553-3560, 2001.

Koldamova RP, Lefterov IM, Ikonomovic MD, Skoko J, Lefterov PI, Isanski BA, DeKosky ST, Lazo JS: 22R-Hydroxycholesterol and 9-cis-Retinoic Acid Induce ATP-binding Cassette Transporter A1 Expression and Cholesterol Efflux in Brain Cells and Decrease Amyloid Secretion. J Biological Chemistry 278(15):13244-13256, 2003.

Kordower JH, Chu Y, Stebbins GT, DeKosky ST, Cochran EJ, Bennett D, Mufson EJ: Loss and Atrophy of Layer II Entorhinal Cortex Neurons in Elderly People with Mild Cognitive Impairment. Annals of Neurology 49:202-213, 2001.

Lambert J-C, Luedecking-Zimmer E, Merrot S, Hayes A, Thaker U, Desai P, Houzet A, Hermant X, Cottel D, Pritchard A, Iwatsubo T, Pasquier F, Frigard B, Conneally PM, Chartier-Harlin M-C, DeKosky ST, Lendon C, Mann D, Kamboh MI, and Amouyel P: Association of 3'-UTR polymorphisms of the oxidized LDL-receptor 1 (OLR1) gene with Alzheimer's disease. Journal of Medical Genetics 40:424-430, 2003.

Lefterov IM, Koldamova RP, Lazo JS: Human bleomycin hydrolase regulates the secretion of amyloid precursor protein. FASEB J. 14(12) :1837-1847, 2000.

Lefterov IM, Koldamova RP, Lefterova MI, Schwartz DR, Lazo JS: Cysteine 73 in Bleomycin Hydrolase Is Critical for Amyloid Precursor Protein Processing. Biochemical and Biophysical Research Communications 283(4): 994-999, 2001.

Lingler, J. H., Martire, L. M., & Schulz, R. (2005). Caregiver-specific outcomes in anti-dementia clinical drug trials: a systematic review and meta-analysis. Journal of the American Geriatrics Society, 53, 6, 983-990.

Lingler JH, Kaufer DI: Cognitive and Motor Symptoms in Dementia: Focus on Dementia with Lewy Bodies. J of the American Academy of Nurse Practitioners 14(9):398-404, 2002.

Lingler JH: Beyond Consent: Ethical Issues in Distinguishing Sexual Activity from Sexual Maltreatment among Women with Dementia. Journal of Elder Abuse and Neglect. 15, 2, 85-102. 2004.

Lopez OL, Becker JT, Klunk W, Saxton J, Hamilton RL, Kaufer DI, Sweet RA, Meltzer CC, Wisniewski S, Kamboh MI, DeKosky ST: Research evaluation and diagnosis of probable Alzheimer's disease over the last two decades: I. Neurology 55:1854-1862, 2000.

Lopez OL, Becker JT, Klunk W, Saxton J, Hamilton RL, Kaufer DI, Sweet RA, Meltzer CC, Wisniewski S, Kamboh MI, DeKosky ST: Research evaluation and diagnosis of possible Alzheimer's disease over the last two decades: II. Neurology 55:1863-1869, 2000.

Lopez OL, Hamilton RL, Becker JT, Wisniewski S, Kaufer DI, DeKosky ST: Severity of cognitive impairment and the clinical diagnosis of AD with Lewy bodies. Neurology 54:1780-1787, 2000.

Lopez OL, Smith G, Becker JT, Meltzer CC, DeKosky ST: The psychotic phenomenon in probable Alzheimer's disease: A positron emission tomography study. J of Neuropsychiatry and Clinical Neurosciences. 12:4, Fall 2000.

Lopez OL, Wisniewski S, Hamilton RL, Becker JT, Kaufer DI, DeKosky ST: Predictors of progression in patients with AD and Lewy bodies. Neurology 54:1774-1779, 2000.

Lopez OL, Zivkovic S, Smith G, Becker JT, Meltzer CC, DeKosky ST: Psychiatric symptoms associated with cortical-subcortical dysfunction in Alzheimer's disease. J of Neuropsychiatry and Clinical Neurosciences 12:4, Fall 2000.

Lopez OL, Smith G, Becker JT, Meltzer CC, DeKosky ST: The Psychotic Phenomenon in Probable Alzheimer's Disease: A Positron Emission Tomography Study. J. Neuropsychiatry Clin Neurosci 13(1):50-55, 2001

Lopez OL, Zivkovic S, Smith G, Becker JT, Meltzer CC, DeKosky ST: Psychiatric Symptoms Associated With Cortical-Subcortical Dysfunction in Alzheimer's Disease. Journal of Neuropsychiatry and Clinical Neurosciences 13:56-60, 2001.

Lopez OL, Becker JT, Kaufer DI, Hamilton RL, Sweet RA, Klunk W, DeKosky ST: Research Evaluation and Prospective Diagnosis of Dementia with Lewy Bodies. Archives of Neurology 59:43-30, 2002

Lopez OL, Becker JT, Kaufer DI, Hamilton RL, Sweet RA, Klunk WE, DeKosky ST. Research Evaluation and Prospective Diagnosis of Dementia With Lewy Bodies. Archives of Neurology, 59:43-46, 2002.

Lopez OL, Becker JT, Wisniewski S, Saxton J, Kaufer DI, DeKosky ST: Cholinesterase Inhibitor treatment alters the natural history of Alzheimer's disease. J Neurol Neurosurg Psychiatry 72:310-314, 2002.

Lopez OL, Becker JT, Sweet R, Klunk W, Kaufer D, Saxton J, Habeych M, DeKosky ST: Psychiatric Symptoms vary with the Severity of Dementia in Probable Alzheimer's Disease. J of Neuropsychiatry and Clinical Neurosciences, 15(3):346-353, 2003.

Lopez OL, Becker JT, Sweet RA, Klunk WE, Kaufer DI, Saxton J, DeKosky ST. Patterns of Change In the Treatment of Psychiatric Symptoms in Patients With Probable Alzheimer's Disease from 1983 to 2000. J of Neuropsychiatry and Clin Neurosci, 15:1 Winter, 2003.

Lopez OL and DeKosky ST: Neuropathology of Alzheimer's Disease and Mild Cognitive Impairment. Rev Neurol 37:155-163, 2003. (Spanish)

Lopez OL, Jagust WJ, DeKosky ST, Becker JT, Fitzpatrick A, Dulberg C, Breitner J, Lyketsos C, Jones B, Kawas C, Carlson M, and Kuller LH: Prevalence and Classification of Mild Cognitive Impairment in the Cardiovascular Health Study Cognition Study: Part 1. Archives of Neurology 60:1385-1393, 2003.

Lopez OL, Jagust WJ, Dulberg C, Becker JT, DeKosky ST, Fitzpatrick A, Breitner J, Lyketsos C, Jones B, Kawas C, Carlson M, and Kuller LH: Risk Factors for Mild Cognitive Impairment in the Cardiovascular Health Study Cognition Study: Part 2. Archives of Neurology 60:1394-1399, 2003.

Luedecking EK, DeKosky ST, Mehdi H, Ganguli M, Kamboh MI: Analysis of genetic polymorphisms in the transforming growth factor- 1 gene and the risk of Alzheimer's disease. Hum Genet 106:565-569, 2000.

Luedecking-Zimmer E, DeKosky ST, Chen Q, Barmada MM, Kamboh MI: Investigation of oxidized LDL-receptor 1 (OLR1) as the candidate gene for Alzheimer's disease on chromosome 12. Hum Genet 111:443-451, 2002.

Luedecking-Zimmer E, DeKosky ST, Nebes R, Kamboh MI: Association of the 3'UTR Transcription Factor LBP-1c/CP2/LSF Polymorphism With Late-Onset Alzheimer's Disease. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics) 117B:114-117, 2003.

Mamo DC, Sweet RA, Mulsant BH, Pollock BG, Miller MD, Stack JA, Begley AE, Reynolds CF: Effect of Nortriptyline and Paroxetine on Extrapyramidal Signs and Symptoms. Am J Geriatr Psychiatry 8:226-231, 2000.

Mamo DC, Sweet RA, Mulsant BH, Rosen J, Pollock BG: Neuroleptic-Induced Parkinsonism in Alzheimer's Disease. Psychiatric Annals. 32(4):249-252, 2002.

Marshall GA, Kaufer DI, Lopez OL, Rao GR, Hamilton RL, DeKosky ST. Right prosubiculum amyloid plaque density correlates with anosognosia in Alzheimer's disease. J Neurol Neurosurg Psychiatry, in press, 2004.

Mathis CA, Bacskai BJ, Kajdasz ST, McLellan ME, Frosch MP, Hyman BT, Holt DP, Wang Y, Huang GF, Debnath ML, Klunk WE: A Lipophilic Thioflavin-T Derivative for Positron Emission Tomography (PET) Imaging of Amyloid in Brain. Bioorganic & Medicinal Chemistry Letters, 12:295-298, 2002.

Mathis CA, Wang Y, Holt DP, Huang G-F, Debnath ML and Klunk WE. Synthesis and Evaluation of 11C-Labeled 6-Substituted 2-Arylbenzothiazoles as Amyloid Imaging Agents. J. Med. Chem. 46:2740-2754, 2003.

Mathis CA, Wang Y, Klunk WE. Imaging ß-Amyloid Plaques and Neurofibrillary Tangles in the Aging Human Brain. Current Pharmaceutical Design (in press) 2004.

Maxwell RA, Sweet RA, Mulsant BH, Rosen J, Kirshner MA, Kastango KB, Pollock BG. Risperidone and 9-Hydroxyrisperidone Concentrations Are Not Dependent on Age or Creatinine Clearance Among Elderly Subjects. J Geriatr Psychiatry and Neurol 15:77-81, 2002.

McKeith IG, Dickson DW, Lowe J, Emre M, O’Brien JT, Feldman H, Cummings J, Duda JE, Lippa C, Perry EK, Aarsland D, Arai H, Ballard CG, Boeve B, Burn DJ, Costa D, Del Ser T, Dubois B, Galasko D, Gauthier S, Goetz CG, Gomez-Tortosa E, Halliday G, Hansen LA, Hardy J, Iwatsubo T, Kalaria RN, Kaufer D, Kenny RA, Korczyn A, Kosaka K, Lee VM-Y, Lees A, Litvan I, Londos E, Lopez OL, Minoshima S, Mizuno Y, Molina JA, Mukaetova-Ladinska EB, Pasquier F, Perry RH, Schulz JB, Trojanowski JQ, Yamada M for the Consortium on DLB: Diagnosis and management of dementia with Lewy bodies. Third report of the DLB consortium. Neurology 65(12):E26-7, 2005.

McKeith I, Mintzer J, Aarsland D, Burn D, Chiu H, Cohen-Mansfield J, Dickson D, Dubois B, Duda J, Feldman H, Gauthier S, Halliday G, Lawlor B, Lippa C, Lopez OL, Machado J, O'Brien J, Playfer J, Reid W (on behalf of IPA Special Expert Meeting Dementia with Lewy bodies): Dementia with Lewy bodies. Lancet-Neurology 3:19-28, 2004.

Meltzer CC, Cantwell MN, Greer P, Ben-Eliezer D, Smith GS, Frank G, Kaye W, Houck PR, Price JC: Does Cerebral Blood Flow Decline in Healthy Aging? A PET Study with Partial-Volume Correction. J. Nucl. Med. 41(11):1842-1848, 2000.

Meltzer CC, Drevets WC, Price JC, Mathis CA, Lopresti B, Greer PJ, Villemagne V, Holt D, Mason NS, Houck PR, Reynolds CF, DeKosky ST, Gender-specific aging effects on the serotonin 1A receptor. Brain Research 895(1-2):9-17, 2001.

Meltzer CC. Neuropharmacology and Receptor Studies in the Elderly. Proceedings from the Second Barcelona-Pittsburgh Conference. Revista de Neurologia 35(8):767-777, 2002.

Meltzer CC, Bell-McGinty S, Scanlon JM. Imaging of Mild Cognitive Impairment. (Exploración del deterioro cognitivo leve por neuroimagen) Proceedings from the Third Barcelona-Pittsburgh Conference. Rev Neurol 37:145-149, 2003. (Spanish)

Mendez OE, Shang J, Jungreis CA, Kaufer DI: Diffusion-Weighted MRI in Creutzfeldt-Jakob Disease: A Better Diagnostic Marker Than CSF Protein 14-3-3? Journal of Neuroimaging MS 13:147-151, 2003.

Minster RL, DeKosky ST, Ganguli M, Belle S, Kamboh MI: Genetic Association Studies of Interleukin-1 (IL-1A and IL-1B) and Interleukin-1 Receptor Antagonist Genes and the Risk of Alzheimer's Disease. Annals of Neurology 48(5):817-818, 2000.

Mirnics ZK, Calafat J, Udby L, Lovelock J, Kjeldsen L, Rothermund K, Sisodia SS, Borregaard N, Corey SJ: Identification of the Presenilins in Hematopoietic Cells with Localization of Presenilin 1 to Neurotrophil and Platelet Granules. Blood Cells, Molecules, and Diseases 28(1):28-38, 2002.

Mufson EJ, Ikonomovic MD, Styren SD, Counts SE, Wuu J, Leurgans S, Bennett DA, Cochran EJ, and DeKosky ST: Preservation of Brain Nerve Growth Factor in Mild Cognitive Impairment and Alzheimer Disease. Archives of Neurology 60:1143-1148, 2003.

Mufson EJ, Ginsberg SD, Ikonomovic MD and DeKosky ST: Human Cholinergic Basal Forebrain: Chemoanatomy and Neurologic Dysfunction. J Chem Neuroanatomy 26:233-242, 2003.

Munro CA, Saxton J, Butters MA: Alcohol Dementia: "Cortical" or "Subcortical" Dementia? Archives of Clinical Neuropsychology 16(6):523-533, 2001.

Munro CA, Saxton J, Butters MA: The Neuropsychological Consequences of Abstinence Among Older Alcoholics: A Cross-Sectional Study. Alcohol Clin Exp Res 24(10):1510-1516, 2000.

Nebes RD, Butters MA, Mulsant BH, Pollock BG, Zmuda MD, Houck PR, Reynolds CF: Decreased working memory and processing speed mediate cognitive impairment in geriatric depression. Psychological Medicine 30:679-691, 2000.

Nebes RD, Vora IJ, Meltzer CC, Fukui MB, Williams RL, Kamboh MI, Saxton J, Houck PR, DeKosky ST, Reynolds CF: The Relationship of Deep White Matter Hyperintensities and Apolipoprotein E Genotype to Depressive Symptoms in Older Adults without Clinical Depression. Am. J. of Psychiatry 158:878-884, 2001.

Nebes RD, Butters MA, Houck PR, Zmuda MD, Aizenstein H, Pollock BG, Mulsant BH, Reynolds CF: Dual-task performance in depressed geriatric patients. Psychiatry Research 102:139-151, 2001.

Nebes RD, Reynolds CF, Boada F, Meltzer CC, Fukui MB, Saxton J, Halligan ED, DeKosky ST: Longitudinal increase in the volume of white matter hyperintensities in late-onset depression. International J of Geriatric Psychiatry 17:526-530, 2002.

Nebes RD, Pollock BG, Houck PR, Butters MA, Mulsant BH, Zmuda MD, Reynolds CF III: Persistence of cognitive impairment in geriatric patients following antidepressant treatment: A randomized, double-blind clinical trial with nortriptyline and paroxetine. J. of Psychiatric Research. 2003, 37, 99-108.

Nightingale MC: Religion, spirituality, and ethnicity: What it means for caregivers of persons with Alzheimer's disease and related disorders. Dementia 2(3):379-391, 2003.

O'Brien JT, Erkinjuntti T, Reisberg B, Roman G, SawadaT, Pantoni L, Bowler JV, Ballard C, DeCarli C, Gorelick PB, Rockwood K, Burns A, Gauthier S, and DeKosky ST: Vascular cognitive impairment. The Lancet Neurology 2:89-98, 2003.

Pandav R, Dodge HH, DeKosky ST, and Ganguli M: Blood Pressure and Cognitive Impairment in India and the United States: A Cross-National Epidemiological Study. Archives of Neurology 60:1123-1128, 2003.

Petersen RC, Stevens JC, Ganguli M, Tangalos EG, Cummings JL, DeKosky ST: Practice parameter: Early detection of dementia: Mild cognitive impairment (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 56:1133-1142, 2001.

Pettegrew JW, Klunk WE, Panchalingam K, McClure RJ, Stanley JA: Molecular insights into neurodevelopmental and neurodegenerative diseases. (Proceedings of the 9th International Symposium on "New Frontiers of Neurochemistry and Biophysics in the Acute and Chronic Neurological Diseases, May, 2000) Brain Research Bulletin 53(4)455-469, 2000.

Pettegrew JW, Levine J, McClure RJ: Acetyl-L-Carnitine Physical-Chemical, Metabolic, and Therepeutic Properties: Relevance for its mode of action in Alzheimer's disease and geriatric depression. Molecular Psychiatr 5(6):771-782,2001.

Pettegrew JW, Panchalingam K, Hamilton RL, McClure RJ: Brain Membrane Phospholipid Alternations in Alzheimer's Disease. Neurochemical Research 26(7):771-782, 2001.

JW, Klunk WE, Panchalingam K, McClure RJ, Stanley JA: Molecular insights into neurodevelopmental and neurodegenerative diseases. (Proceedings of the 9th International Symposium on "New Frontiers of Neurochemistry and Biophysics in the Acute and Chronic Neurological Diseases, May, 2000) Brain Research Bulletin 53(4)455-469, 2000.

Pettegrew JW, Levine J, McClure RJ: Acetyl-L-Carnitine Physical-Chemical, Metabolic, and Therepeutic Properties: Relevance for its mode of action in Alzheimer's disease and geriatric depression. Molecular Psychiatr 5(6):771-782,2001.

Pettegrew JW, Panchalingam K, Hamilton RL, McClure RJ: Brain Membrane Phospholipid Alternations in Alzheimer's Disease. Neurochemical Research 26(7):771-782, 2001.

Pollock BG, Ferrell RE, Mulsant BH, Mazumdar S, Miller M, Sweet RA, Davis S, Kirshner MA, Houck PR, Stack JA, Reynolds CF, Kupfer DJ: Allelic Variation in the Serotonin Transporter Promoter Affects Onset of Paroxetine Treatment Response in Late-Life Depression. Neuropsycho-pharmacology 23:587-590, 2000.

Pollock BG, Mulsant BH, Rosen J, Sweet RA, Mazumdar S, Bharucha A, Marin R, Jacob NJ, Huber KA, Kastango KB, Chew ML. Comparison of Citalopram, Perphenazine and Placebo for the Acute treatment of Psychosis and Behavioral Disturbances in Hospitalized, Demented Patients. American Journal of Psychiatry, 159:460-465, 2002.

Price JC, Lopresti BJ, Mason NS, Holt DP, Huang Y, Mathis CA. Analyses of [18F]altanserin bolus injection PET data I: Consideration of radiolabeled metabolites in baboons. Synapse 2001; 41:1-10.

Price JC, Lopresti BJ, Mason NS, Holt DP, Meltzer CC, Smith GS, Gunn RN, Huang Y, Mathis CA. Analyses of [18F]altanserin bolus injection PET data II: Consideration of radiolabeled metabolites in humans. Synapse 2001; 41:11-21.

Ranganathan S, Scudiere S, Bowser R: Hyperphosphorylation of the retinoblastoma gene product and altered subcellular distribution of E2F-1 during Alzheimer's disease and amyotrophic lateral sclerosis. J of Alzheimer's Disease 3:377-385, 2001.

Richards SS, Sweet RA: Treating Psychosis in Alzheimer's Disease. Alzheimer's Disease Management Today 2(3):3-9, 2000.

Saxton J, Munro CA, Butters MA, Schramke C, McNeil MA: Alcohol, Dementia, and Alzheimer's Disease: Comparison of Neuropsychological Profiles. J Geriatr Psychiatry Neurol 13:141-149, 2000.

Saxton J, Ratcliff G, Munro C, Coffey CE, Becker JT, Fried L, Kuller L: Normative Data on the Boston Naming Test and Two Equivalent 30-Item Short Forms. The Clinical Neuropsychologist 14(4):526-534, 2000.

Saxton J, Ratcliff G, Newman A, Belle S, Fried L, Yee J, Kuller L: Cognitive Test Performance and Presence of Subclinical Cardiovascular Disease in the Cardiovascular Health Study. Neuroepidemiology, 19:312-319, 2000.

Saxton J, Munro CA, Butters MA, Schramke C, McNeil MA: Alcohol, Dementia, and Alzheimer's Disease: Comparison of Neuropsychological Profiles. J. Geriatr Psychiatry Neurol 13:141-149, 2000.

Solai LK, Pollock BG, Mulsant BH, Frye RF, Miller MD, Sweet RA, Kirshner M, Sorisio D, Begley A, Reynolds III CF: Effect of Nortriptyline and Paroxetine on CYP2D6 Activity in Depressed Elderly Patients. Journal of Clinical Psychopharmacology 22(5)1-6. 2002.

Styren SD, Hamilton RL, Styren GC, Klunk WE: X-34, A Fluorescent Derivative of Congo Red: A Novel Histochemical Stain for Alzheimer's Disease Pathology. J. of Histochemistry & Cytochemistry 48(9):1223-1232, 2000.

Sukonick DL, Pollock BG, Sweet RA, Mulsant BH, Rosen J, Klunk WE, Kastango KB, DeKosky ST, Ferrell RE: The 5-HTTPR*S/*L Polymorphism and Aggressive Behavior in Alzheimer's Disease. Arch Neurol 58:1425-1428, 2001.

Sweet RA, Hamilton RL, Healy MT, Wisniewski SR, Henteleff R, Pollock BG, Lewis DA, DeKosky ST: Alterations of Striatal Dopamine Receptor Binding in Alzheimer Disease are Associated With Lewy Body Pathology and Antemortem Psychosis. Archives of Neurology 58:466-472, 2001.

Sweet RA, Hamilton RL, Lopez OL, Klunk WE, Wisniewski SR, Kaufer DI, Healy MT, DeKosky ST: Psychotic Symptoms in Alzheimer's Disease Are Not Associated With More Severe Neuropathologic Features. International Psychogeriatrics 12(4):547-558, 2000.

Sweet RA, Pollock BG, Sukonick DL, Mulsant BH, Rosen J, Klunk WE, Kastango KB, DeKosky ST, Ferrell RE: The 5-HTTPR Polymorphism Confers Liability to a Combined Phenotype of Psychotic and Aggressive Behavior in Alzheimer's Disease. International Psychogeriatrics 13(4):401-409, 2001.

Sweet RA, Taking a New Look at Psychosis In Alzheimer Disease. Psychiatric Times. Special Report 19(11), 37-38, 2002.

Sweet RA, Kamboh MI, Wisniewski SR, Lopez OL, Klunk WE, Kaufer DI, DeKosky ST: Apolipoprotein E and Alpha-1-Antichymotrypsin Genotypes Do Not Predict Time To Psychosis In Alzheimer's Disease. Neurology, 15:24-30, 2002.

Sweet RA, Nimgaonkar VL, Devlin B, Lopez OL, DeKosky ST: Increased familial risk of the psychotic phenotype of Alzheimer disease. Neurology 58:907-911, 2002.

Sweet RA, Panchalingam K, Pettegrew JW, McClure RJ, Hamilton RL, Lopez OL, Kaufer DI, DeKosky ST, Klunk WE: Psychosis in Alzheimer's disease: postmortem magnetic resonance spectroscopy evidence of excess neuronal and membrane phospholipid pathology. Neurobiology of Aging 23(4):547-553, 2002.

Sweet RA: Taking a New Look at Psychosis in Alzheimer's Disease. Psychiatric Times 19(11), 2002.

Sweet RA, Nimgaonkar VL, Devlin B, Jeste DV. Psychotic symptoms in Alzheimer disease: evidence for a distinct phenotype. Molecular Psychiatry 8:383-392, 2003.

Thulborn KR, Martin C, Voyvodic JT. Functional MR imaging using a visually guided saccade paradigm for comparing activation patterns in patients with probable Alzheimer's disease and in cognitively able elderly volunteers. American Journal of Neuroradiology 2000;21:524-531.

Walker MP, Schlaberg R, Hays AP, Bowser R, Lipkin WI: Absence of Echovirus Sequences in Brain and Spinal Cord of Amyotrophic Lateral Sclerosis Patients. Ann Neurol 49:249-253, 2001.

Wang X, Luedecking EK, Minster RL, Ganguli M, DeKosky ST, Kamboh MI: Lack of association between 2-macroglobulin polymorphisms and Alzheimer's disease. Hum Genet 108:105-108:2001.

Wang X, DeKosky ST, Ikonomovic M, Kamboh MI: Distribution of plasma 1- antichymotrypsin levels in Alzheimer disease patients and controls and their genetic controls. Neurobiology of Aging, 23:377-382, 2002.

Wang X, DeKosky ST, Luedecking-Zimmer E, Ganguli M, Kamboh MI: Genetic variation in 1-antichymotrypsin and its association with Alzheimer's disease. Human Genetics 110:356-365, 2002.

Wang Y, Klunk WE, Huang GF, Debnath ML, Holt DP, Mathis CA: Synthesis and Evaluation of 2- (3'-lodo-4'-aminophenyl)-6-hydroxybenzothiazole for In Vivo Quantitation of Amyloid Deposits in Alzheimer's Disease. J of Molecular Neuroscience 19:11-16, 2002.

Wang Y, Mathis CA, Huang G-F, Holt DP, Debnath ML, Klunk WE. Synthesis and C-11-labelling of (E,E)-1-(3',4'-dihydroxystyryl)-4-(3'-methoxy-4'-hydroxystyryl) benzene for PET imaging of amyloid deposits. J. Labeled Compd and Radiopharm. 45: 647-664, 2002.

Wang Y, Mathis CA, Huang G-F, Debnath ML, Holt DP, Shao L, and Klunk WE. Effects of Lipophilicity on the Affinity and Non-Specific Binding of Iodinated Benzothiazole Derivatives. J. Mol. Neurosci. 20:255-260, 2003.

Whyte EM, Mulsant BH, Butters MA, Qayyum M, Towers A, Sweet RA, Klunk W, Wisniewski S, DeKosky ST: Cognitive and Behavioral Correlates of Low Vitamin B12 Levels in Elderly Patients With Progressive Dementia. Am J of Geriatric Psychiatry 10:321-327, 2002.

Williams KV, Price JC, Kelley DE. Interactions of impaired glucose transport and phosphorylation in skeletal muscle insulin resistance: a dose-response assessment using positron emission tomography. Diabetes 2001; 50(9):2069-79.

Zhu JH, Kulich SM, Oury TD, Chu CT: Cytoplasmic Aggregates of Phosphorylated Extracellular Signal-Regulated Protein Kinases in Lewy Body Diseases. Am J of Pathology 161(6):2087-2098, 2002.

Zhu JH, Guo F, Shelburne J, Watkins S, Chu CT: Localization of Phosphorylated ERK/MAP Kinases to Mitochondria and Autophagosomes in Lewy Body Diseases. Brain Pathology 13(4):473-481, 2003.

Zivkovic S, Rovira MBi, Lopez OL: Creutzfeldt-Jakob Disease. Revista de Neurologica, 32(12):1171-1179, 2000.

Zuin D, Ortiz H, Boromel D, Lopez OL: Motor vehicle crashes and abnormal driving behaviours in patients with dementia in Mendoza, Argentina. European Journal of Neurology 9:29-34, 2002.

Monographs and Book Chapters


Aizenstein HJ, Reynolds CF III. The Treatment of Geriatric Depression: Progress and Challenges. The Economics of Neuroscience 3(7)58-62, 2001.

Becker JT, Aizenstein H, Butters MA: Structural and Functional Neuroimaging Findings in Normal and Pathological Aging. In: Bush SS, Martin TA, editors. Geriatric Neuropsychology: Fundamentals for Practice. Hove: Taylor & Francis, 2005, 141-164.

DeKosky ST: Epidemiology and pathophysiology of Alzheimer's disease. In: M. Quan (Ed). Clinical Cornerstone. Belle Mead, NJ: Excerpta Medica, 15-26, 2001.

DeKosky ST, Kaufer DI and Lopez OL: The dementias. In: Neurology in Clinical Practice, 4th Edition . W.G. Bradley, R.B. Daroff, G.M. Fenichel, and J. Jankovic, Editors. Philadelphia: Butterworth Heinemann, 1901-1951, 2004.

Kaufer, DI: Alzheimer's disease: Focus on the cholinergic system. In: Perry E, Ashton H, Young A (eds). Neurochemistry of Consciousness. John Benjamins Publishing Company, Philadelphia. Vol 36, pp 229-245.

Kaufer DI, Cummings JL: Delirium and Dementia: An Overview. In: Geinberg T, Farah M. (eds). Behavioral Neurology and Neuropsychology, 2nd Ed. McGraw-Hill, In Press, 2004.

Kaufer DI, DeKosky ST: Diagnostic Classifications: Relationship to the Neurobiology of Dementia. In: Charney DS, Bestler EJ, Bunney BS (Eds). Neurobiology of Mental Illness, 2nd. Oxford University Press, In Press, 2004.

Klunk WE, Engler H, Nordberg A, Bacskai BJ, Wang Y, Price JC, Bergstrom M, Hyman BT, Langstrom B, and Mathis CA. Imaging the pathology of Alzheimer's disease: amyloid-imaging with positron emission tomography. CC Meltzer, ed. Neurological Applications of PET. Neuroimaging Clinics of North America, W.B. Saunders Co., Philadelphia, 2003 13(4):781-790.

Lingler JH, Schulz R: Do the Benefits of Anti-Dementia Drugs Extend to Caregivers? In B Vellas (ed.), Research and Practice in Alzheimer's Disease and Cognitive Decline, Volume 11, Paris: Seri Publishing, pp 322-327, 2005.

Lopez OL: Neuroradiological studies in patients with mild cognitive impairment. Continua Neurologica 3:28-36, 2000.

Lopez OL: Mild Cognitive Impairment of early Alzheimer's disease. In: J.M. Martinez-Labe, Z.S. Khachaturian, Foro Alzheimer XXI. Barcelona, Spain, Masson Publishers pp 195-198, 2001.

Lopez OL: The relationship between dementia with Lewy bodies and Alzheimer's disease. In: J.M. Martinez-Labe, Z.S. Khachaturian, Foro Alzheimer XXI. Barcelona, Spain, Masson Publishers pp 199-206, 2001.

Lopez OL: The use of biomarkers in the diagnosis of Alzheimer's disease. In: J.M. Martinez-Labe, Z.S. Khachaturian, Foro Alzheimer XXI. Barcelona, Spain, Masson Publishers pp 207-218, 2001.

Lopez OL: The Neurobiological basis of behavioral symptoms in Alzheimer's disease and related dementias. In: Alberca R (Ed). Treatment of behavioral disorders in Alzheimer's disease and other neurological processes. Madrid, Editorial Panamericana. pp 47-63, 2001.

Lopez O, Bell McGinty, S. Memory Dysfunction and Drug Treatment. To appear in D.J. Ekerdt (Ed.) The MacMillan Encyclopedia of Aging, MacMillan Reference In press, 2004.

Lopez OL, Bell S: Neurobiological Treatment of Alzheimer's Disease. In: Morris R, Becker JT (Eds). The Cognitive Neuropsychology of Alzheimer's disease. Oxford University Pres, Oxford (U.K.), In Press, 2004.

Lopez OL, DeKosky ST: Neurobiology of Alzheimer's Disease. In: Gershon S, Soares J (Eds). The Handbook of Medical Psychiatry. New York, Marcel Dekker, Inc., 2003:537-552.

Lopez OL, Becker JT: The Natural History of Alzheimer's Disease. In: Morris R, Becker JT (Eds). The Cognitive Neuropsychology of Alzheimer's disease. Oxford University Pres, Oxford (U.K.). In Press, 2004.

Lopez OL, Becker JT: Treatment of Alzheimer's Disease. Neurologia (Spain), 35:850-859, 2002.

Lopez OL: Classification of mild cognitive impairment in a population study. Neurologia (Spain), 37(2):140-144, 2003. (Spanish)

Lopez OL, DeKosky ST: Neuropathology of Alzheimer's disease and Mild Cognitive Impairment. Neurologia (Spain) 37:155-163, 2003. (Spanish)

Lopez OL, Becker JT: Factors that Modify the Natural Course of Alzheimer's Disease. Neurologia (Spain), 37:149-155, 2003. (Spanish)

McClure RJ, Panchalingam K, Klunk WE, Pettegrew JW: Brain Membrane and Energy Metabolism: Magnetic Resonance Spectroscopy Analyses. In: Encyclopedia of Aging: A comprehensive Resource in Gerontology and Geriatrics, Third Edition. Springer Publishing Company. Pp 133-135, 2001.

Meltzer CC, Boada F, Pettegrew JW, Scanlon JM. Imaging Neurobehavioral Disorders. In: Latchaw, Kucharczyk, Mosley, eds. Advanced Imaging and Image-Guided Therapy of the Nervous System. Harcourt Publishing. In Press, 2002.

Meltzer CC (Guest Editor). Neurological Applications of Positron Emission Tomography. Neuroimaging Clinics of North America, W.B. Saunders Co., Philadelphia, Volume 13(4), 2003.

Meltzer CC, Becker JT, Price JC, Moses-Kolko, E. Positron emission tomography imaging of the aging brain, In: CC Meltzer, ed. Neurological Applications of PET. Neuroimaging Clinics of North America, W.B. Saunders Co., Philadelphia. 13(4):759-768, 2003.

Selected Abstracts


Abrahamson EE, Ikonomovic MD, DeKosky ST: Apolipoprotein D Marks Alzheimer-Like Pathology in Human Victims of Traumatic Brain Injury. J Neurotrauma 20(10):1116, 2003.

Abramson EE, Ikonomovic MD, Koldamova RP, Lefterov IM, Isanski BA, Lazo JS, DeKosky ST: Increased Expression of Cholesterol Transporter ABCA1 and Amyloid Precursor Protein After Traumatic Brain Injury. Washington, DC: Society for Neuroscience, 2003.

Aizenstein H, Clark K, Butters M, Cochran J, Stenger VA, Meltzer C, Reynolds C, Carter C: The BOLD Hemodynamic Response in Healthy Aging. Abstract. Poster presented at Human Brain Mapping 2003.

Bohnen NI, Kaufer DI, Lopresti B, Koeppe RA, Mathis CA, DeKosky ST, Moore RY: Cerebral Acetylcholinesterase Activity in Patients with Parkinson's Disease With and Without Demenita and Alzheimer's disease. Abstract. J. Nucl Med 43(5):63P, 2002.

Bohnen NI, Kaufer DI, Lopresti B, Koeppe RA, Meltzer CC, Mathis CA, Moore RY, DeKosky ST: Clinical Regional Cerebral Acetylcholinesterase (ACHE) and Glucose Metabolic Changes After Donepezil Therapy in Patients with Alzheimer's Disease (AD). Abstract. J. Nucl Med 43(5):63P, 2002.

Bohnen NI, Kaufer DI, Ivanco LS, Hendrickson R, Lopresti B, Davis JG, Mathis CA, Meltzer CC, Moore RY, DeKosky ST: Relationship Between Acetylcholinesterase PET Imaging and Clinical Response to Donepezil Treatment in Alzheimer's Disease. J Nucl Med: 44(suppl):16P, 2003.

Bohnen N, Kaufer D, Lopresti B, Mathis C, Moore R, DeKosky S: Brain Region-Selective Inhibition of Acetylcholinesterase Activity by Donepezil in AD. Neurology: 60(suppl. 1): A412-413, 2003.

Bohnen N Kaufer D, Ivanco L, Hendrickson R, Lopresti B, Mathis C, DeKosky ST, Moore R: Syndromal Differences in Neurobehavioral Correlates of Cholinergic Denervation in Alzheimer's and Parkinson's Disease. Neurology: 60(suppl 1): A143, 2003.

Butters MA, Sweet RA, Mulsant BH, Kamboh MI, Pollock BG, Nebes RD, Begley AE, DeKosky ST, Reynolds CF: APOE is associated with age-of-onset, but not cognition, in late-life depression. Annual meeting of the American Association of Geriatric Psychiatry, February, 2002.

DeKosky ST, Mufson EJ, Ikonomovic MD: Reduction of Choline Acetyltransferase Activity in Visual Cortex Marks early Alzheimer's Disease. Soc Neurosci Abstr, 202:15, 2003.

Demidovich J, Pittman CA, Hamilton RL. Altered calpain proteolysis of mutant alpha-synuclein. Honors Thesis presentation, Univ. Pitt, March 2002.

Desai PP, Ikonomovic MD, Hamilton RL, DeKosky ST, Kamboh MI. Apolipoprotein D in Alzheimer's Disease: implications for amyloid pathology. Soc. for Neuroscience, Orlando, 2002.

Garb S, Hamilton RL. Sequestration of soluble alpha-synuclein in Lewy body Variant of Alzheimer's Disease. Abstract. Soc for Neuroscience, Orlando, 2002.

Hamilton R: The Other Dementias: the Neuropathology of the Non-Alzheimer's Disease Dementias. Presented at "Dementia Today - the Third Pittsburgh - Barcelona Alzheimer's Disease Conference" Barcelona, Spain, October 22-27, 2002.

Happ M, Beeber A, Lingler JH, Twigg P, Kagan S: Our Social Selves: Conceptual, Ethical and Empirical Perspectives on Health-Related Decision-Making Within Aging Families. Presented at the Gerontological Society of America Annual Meeting in November, 2003. The Gerontologist 43(1):572, 2003.

Ikonomovic MD, Abrahamson EE, Paljug WR, DeKosky ST: Changes in Nicotinic Receptor Subunits in Temporal Cortex from Subjects with Mild Cognitive Impairments. Soc Neurosci Abstr, 203:21, 2003.

Isanski BA, Ikonomovic MD, Abrahamson EE, Uz T, Manev H, DeKosky ST: 5-Lipoxygenase Immunoreactivity in Hippocampus of Alzheimer's Patients. Soc Neurosci Abstr, 526:10, 2003.

Kaufer DI, Bohnen NI, Lopresti B, Mathis CA, Moore RY, DeKosky ST: PET Acetylcholinesterase Imaging Correlates with Clinical Response to Donepezil Treatment in Parkinsonian Dementia. Neurology 60(Suppl 1):A414, 2003.

Kaufer DI, Sarles, CE., Saxton JA, Becker JT,. DeKosky ST. Certainty-Indexed Memory Assessment in AD, normal aging and MCI. Neurology 60(Suppl 1):A202, 2003.

Lopez OL, Becker JT, Cook SE, Sweet RA, Klunk W, Kaufer DI, Dekosky ST. A Subgroup Analysis of the Association Between Depression and Death in Alzheimer's Disease. Annals of Neurology 54 (7), S67, 2003.

Marshall GA, Kaufer DI, Lopez OL, Rao GR, Hamilton RL, DeKosky ST: Neuropathological Correlate of Anosognosia in Alzheimer's Disease. Neurology 60(Suppl 1):A196-197, 2003.

Meltzer CC, Price JC, Mathis CA, Butters MA, Ziolko SK, Mazumdar S, Houck PR, Reynolds RF: Serotonin 1A Receptor Binding and Treatment Response in Late Life Depression. American Society of Neuropsychopharmacology, San Juan, Puerto Rico, December 7-11, 2003 (accepted).

Mizukami K, Ikonomovic MD, Kamma H, Ishikawa M, Hidaka S, Iwakiri M, DeKosky ST, Asada T: Immunohistochemical Study of the hnRNP B1 in the Hippocampus of Subjects with Alzheimer's Disease. Soc Neurosci Abstr 203:8, 2003.

Pettegrew JW, Panchalingam K, Stanley JA, McClure RJ: 31P and 1H MRSI Studies of Psychosis in Alzheimer's Disease. Submitted, June, 2001.

Perez-Madrinan GM, Cook SE, Saxton JA, Miyahara S, Lopez OL, Kaufer DI, Aizenstein HJ, DeKosky ST, Sweet RA: Psychosis in Alzheimer's Disease: Excess Cognitive Impairment is Restricted to the Misidentification Subtype. Presented at the 16th Annual Meeting of the American Association for Geriatric Psychiatry, Honolulu, Hawaii, 2003.

Prasad KMR, Davis SW, Becker JT, Keshavan MS, Sweet RA: Neurobiological Substrates of Alzheimer's Disease with Psychosis: An Exploratory Study of Structural MRI using Voxel-Based Morphometric Approach Program number 203.15. Washington, DC: Society for Neuroscience, 2003.

Sweet RA, Butters MA, Hamilton RL, Mulsant BH, Lopez OL, Pollock BG, DeKosky ST, Reynolds CF: Neuropathology Of Late Life Mood Disorders. American College of Neuropsychopharmacology, 2003.

Sweet RA, Hamilton RL, DeKosky ST, Nimgaonkar VL, Lopez OL, Pollock BG, Wisniewski SR, Lewis DA: Striatal dopamine receptor binding in Alzheimer's disease: Association with Lewy body pathology and psychosis. Proceedings, 13th Annual meeting of the American Association for Geriatric Psychiatry, Miami Beach FL, March 2000.

Sweet RA, Umapathy C, Nimgoankar VL, Kamboh MI, Lopez OL, DeKosky ST: Role for Norepinephrine in Treatment of Apathy in Dementia. Proceedings, 13th Annual meeting of the American Association for Geriatric Psychiatry, Miami Beach, FL, March 2000.

Sweet RA, Hamilton RL, Lopez OL, Klunk WE, Wisniewski SR, DeKosky ST: No Increased Severity of Neuropathologic Features in Alzheimer's Disease with Psychosis. Biological Psychiatry. 47(8S):141S, 2000.

Sweet RA, Kamboh IM, Wisniewski SR, Lopez OL, Klunk WE, Kaufer DI, DeKosky ST. APOE And ACT Genotypes Do Not Predict Time To Psychosis In Alzheimer's Disease. Abstracts, Society for Neurocience, 26:1828, 2000.

Sweet RA, Klunk WE, Pettegrew JW, Hamilton RL, Lopez O, Wisniewski SR, DeKosky ST: Evidence of Increased Neuronal Dysfunction in Alzheimer's Disease with Psychosis. Biological Psychiatry, 47(8S):141S, 2000.

Wilson, RK, Luedecking-Zimmer EK, Kamboh MI, DeKosky ST, Hamilton RL. Association of the ApoE4 allele and Lewy bodies in Alzheimer's Disease. AANP, Denver 2002 (JNEN 61: 455, 2002).