Patients & Caregivers / Clinical Trials/Research Studies

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Clinical Trials/Research Studies - Recruiting


Communication about Type 2 Diabetes Treatment in Older Adults with Memory Problems

Description: This study is investigating how diabetes treatment goals and medication decisions are made for older adults with both Type 2 Diabetes Mellitus (T2DM) and memory problems. We will be interviewing 12 informal (unpaid) caregivers of older adults with both T2DM and memory problems.

Study Length: Participation involves one telephone interview that takes 30-60 minutes. Participants will be compensated $40 for completing the interview.

Study Requirements
You may be eligible if you:
  • provide informal care to a spouse, relative, or friend who is 65 years of age or older and has both T2DM and memory problems
  • attend medical appointments with the person for whom you care
  • are age 18 or older
For more information, please contact: Loren Schleiden at 724-766-0361 or ljs24@pitt.edu



EXPEDITION 3 Clinical Trial

Description: This study will test the idea that the investigational medication solanezumab will slow the cognitive and functional decline of Alzheimer's Disease (AD) as compared with placebo in participants with mild AD.

Study Length: Approximately 18 months

Study Requirements
  • Individuals with a diagnosis of mild Alzheimer’s disease
  • Ages 55 – 90
  • A study partner who will accompany the participant to all clinic visits
Contact:
Carolyn Rickard at 412-692-2707 mishlercj@upmc.edu or
MaryAnn Oakley at 412-692-2721 or oakleym@upmc.edu



Medication Study for the Treatment of Agitation in Moderate to Severe Alzheimer's Disease

Description: The purpose of this study is to determine whether an investigational medication (ELND005) is effective for reducing behaviors in people with moderate to severe Alzheimer's disease who have agitation/aggression.

Study Length: 12 Weeks

Study Requirements
  • Diagnosis of moderate to severe Alzheimer's disease with behavior problems/agitation.
  • A study partner who will accompany the participant to all clinic visits.
Contact: MaryAnn Oakley at 412-692-2721 or oakleym@upmc.edu



Objective Evaluation of Family Caregiving Study

Description: The goal of this study is to learn how family caregivers deal with dementia-related behavior and how they respond to suggestions for handling these situations at home. Participants will be asked to wear a video device at home to capture daily interactions with their family member with dementia.

Study Length: 3-4 months

Study Requirements
  • Family caregiver age 21 or older who lives with and provides care to a person with moderate to severe dementia
  • Person age 50 or older with moderate or severe dementia whose behavior is difficult for the caregiver
  • Willing to engage in all study activities at home and by phone
Contact: MaryAnn Oakley at 412-692-2721 or oakleym@upmc.edu