Perceptual Memory Study
Description: The goal of this research study is to learn more about the neural bases of perceptual decision making, and in doing so, to better understand how memory is affected in aging. Using functional magnetic resonance imaging (fMRI), this study will examine changes in brain function while participants perform cognitive tests. The fMRI scan and test results will help researchers gain insight into which parts of the nervous system are involved in different aspects of the tests.
Study Requirements: Individuals 65 - 85 years of age who are currently experiencing progressive cognitive deficits (Mild Cognitive Impairment) -OR- individuals who are cognitively healthy.
Study Length: One visit (3 - 4 hours)
Contact: MaryAnn Oakley at 412-692-2721 or oakleym@upmc.edu
Alzheimer Disease Neuroimaging Study 2 – (ADNI2)
Description: The goal of this study is to determine whether imaging of the brain (through MRI, PET and amyloid imaging scans) can help predict the onset and monitor the progression of cognitive change. The study will test blood and cerebrospinal fluid (from lumbar punctures) to determine if biomarkers can predict and monitor the disease.
Study Length: 54 months
Study Requirements:
- Between 55 and 90 years of age
- Study partner to accompany to all clinical visits
- Either have a diagnosis of early Alzheimer's disease, Mild Cognitive Impairment (MCI), or are cognitively normal
3M Study - Maximizing Medication Management
Description: This study will examine the effect of a new program for teaching family caregivers about managing and administering medications to persons with cognitive impairment.
Study Requirements: family/informal caregiver caring for a friend or family member who needs help managing their medications or a participant who has difficulty remembering and needs help managing medications and has at least one health condition that requires medication management.
Study Length: approximately 6 months
Contact: MaryAnn Oakley at 412-692-2721 or oakleym@upmc.edu