ADRC – Call for Pilot Proposals for Researchers

ADRC Seed Monies Grant Program

Funding Period: April 1, 2018 to March 31, 2019

Introduction: One of the research missions of the Alzheimer Disease Research Center (ADRC) at the University of Pittsburgh is to fund pilot grants to stimulate new and innovative research relevant to Alzheimer’s disease. Types of research can range from basic science to psychosocial in methodology, with particular attention given to novel approaches. Proposed research may involve humans, other animals or in vitro studies. The investigator is responsible for obtaining appropriate Institutional Review Board or Animal Care and Use Committee approval for the proposal. The patient population, clinical, and neuropathological databases of the ADRC are available resources for approved proposals. Additional resources include the database from the National Alzheimer Coordinating Center (NACC). Priority will be given to studies which have the highest chance of leading to subsequent external peer reviewed funding. Applications must clearly state the significance and innovation of the proposed research to Alzheimer’s disease or related disorders.

Criteria for Review: The following will be considered in evaluating the merit of a proposal:

• Soundness of scientific principles.
• Novelty of the scientific approach.
• Scientific merit.
• Likelihood of providing new and valuable insights into possible causes of treatment of Alzheimer’s disease
• Background and experience of the investigator(s)
• Adequacy of the resources and environment.
• Appropriateness of the budget for the proposed work.
• Strong likelihood that the pilot work will lead to subsequent extramural peer reviewed funding.

Eligibility: Applicants must be full-time faculty and post-doctoral fellows of the University of Pittsburgh. Post-doctoral fellows must have a letter of support from their mentor and department chair indicating they will be at the University through 2019. Previous recipients of ADRC seed monies are not eligible.

Budget Limitations: Direct cost budgets up to $25,000 will be considered. There is no allowance for travel, tuition, publication costs or major equipment. Please contact the ADRC Administrator, Leslie Dunn, MPH (dunnlo@upmc.edu) with budget questions.

APPLICATION PROCESS:

  • Letter of Intent: A brief description of the proposed pilot study should be e-mailed to Leslie Dunn, MPH, Center Administrator (dunnlo@upmc.edu) by October 6, 2017. Please include title of the proposal, names of investigators/co-investigators, brief description of project, and a brief statement of relevance of the proposed research to the field.
  • Investigators invited to submit a full proposal will be notified by October 11, 2017.
  • Deadline: Applications must be received no later than October 27, 2017 with funding to start April 1, 2018. (Please follow application guidelines.)

Application Guidelines:
The proposal should consist of the following sections:

  • Title Page (ADRC version. Please request this document from ADRC Administration.)
  • Abstract (Project Summary – Form Page 2)
  • Budget and Budget Justification (PHS 398 Form Page 4 and form Page 5)
  • Biographical Sketch(es) (New Biosketch format – Rev 11/16 approved thru 10/31/18)
  • Resources and Environment
  • Other Support
  • Research Plan
    1. Introduction to Application (Not applicable)
    2. Specific Aims
    3. Research Strategy: Significance; Innovation and Approach (include Preliminary Studies if applicable as well as sections for approaches to be taken to ensure robust and unbiased results, and opportunities for training and professional development)
    4. Bibliography and References Cited
    5. Protection of Human subjects
    6. Data Safety Monitoring Plan, if applicable
    7. Inclusion of Women and Minorities
    8. Targeted/Planned Enrollment Table, if applicable
    9. Inclusion of children
    10. Vertebrate Animals
    11. Select Agent Research
    12. Multiple PD/PI Leadership Plan (Not applicable)
    13. Consortium/Contractual Arrangements
    14. Letters of Support (e.g., Consultants)
    15. Resource Sharing Plan(s)
    16. Authentication of Key Biological and/or Chemical Resources, if applicable

Please provide a list of three prospective reviewers. The specific aims and hypotheses are limited to one page and the research strategy is limited to a total of six single-spaced pages based on PHS 398 (Rev. 03/2016) format and guidelines. Abstract, budget, and biographical sketches sections should be on the standard forms for PHS grants (Rev. 03/2016 through 10/31/18). http://grants.nih.gov/grants/funding/phs398/phs398.html

Send application materials:

Via e-mail to adrcadmin@upmc.edu (Send Word documents. No PDFs please.)

Also send hard copy of the application to:

Leslie Dunn, MPH, ADRC Administrator
Alzheimer Disease Research Center
4-West UPMC Montefiore Hospital
200 Lothrop Street
Pittsburgh, PA 15213

For further information: Interested applicants should discuss potential submission with:
Center Director, Oscar L. Lopez, M.D., lopezol@upmc.edu
Center Co-Director, William E. Klunk, M.D., Ph.D., klunkwe@upmc.edu or
Center Administrator, Leslie Dunn, MPH, (412) 692-2731, dunnlo@upmc.edu
University of Pittsburgh, School of medicine
Alzheimer Disease Research Center
4-West UPMC Montefiore, 200 Lothrop Street
Pittsburgh, PA 15213

Download this document (PDF)

 

Share This:
FacebookTwitterGoogle+Email