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The University of Pittsburgh Alzheimer's Disease Research Center

The University of Pittsburgh Alzheimer Disease Research Center (ADRC) is one of the nation’s leading research centers specializing in the diagnosis of Alzheimer’s disease and related disorders. Through outpatient evaluations, participants and their families receive state-of-the-art diagnostic assessments and contribute to the scientific study of Alzheimer’s disease.

Senior moments or something more?
You walk into a room and forget why you entered in the first place. You can’t quite place a name with a face, or you fail to recall the name of an actor you’ve seen on television recently.  read more »

The Andy Warhol Museum Teams
Up with Pitt’s Alzheimer Disease Research Center

Click here to learn more about the Alzheimer Disease Research Center's partnership with the Andy Warhol Museum.»
We are currently recruiting participants for :

Noble Study

Description: This is a clinical study to evaluate an investigational drug in mild to moderate Alzheimer's disease. The investigational drug may work by protecting brain cells which could result in improved memory. adcs.org

Study Length: 14 months

Study Requirements
  • 55-85 years of age
  • Diagnosis of Alzheimer's disease (Mild-Moderate)
  • A study partner who will accompany the participant to all clinic visits
  • Weight of no more than 220lbs
  • Taking certain memory medication(s) for 6 months
Thomas Baumgartner at 412-692-2716 or baumgartnertc@upmc.edu or
MaryAnn Oakley at 412-692-2721 or oakleym@upmc.edu

A4 Study

Description: The Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease Trial, or A4 Study, is among a new generation of clinical trials being developed to test therapies that might prevent, or at least delay the onset of, Alzheimer's disease in cognitively normal people who may be at risk as evidenced by a PET scan. a4study.org

Study Length: 3 years

Study Requirements
  • 65 to 85 years of age
  • Normal thinking and memory abilities
  • Have a study partner with whom you have contact at least once a week who can answer questions about you once a year (contact may be in person or by phone) willing and able to receive IV infusions of the investigational treatment (solanezumab) or a placebo every 4 weeks for 3 years
MaryAnn Oakley at 412-692-2721 or oakleym@upmc.edu or
Katy Zorich at 412-692-2730 or orchowskik3@upmc.edu

STARBEAM Study (Lundbeck)

Description: The primary objective of this study is to establish the efficacy of an investigational medication (Lu AE58054) as adjunctive therapy to Donepezil for symptomatic treatment of patients with mild-moderate Alzheimer's disease.

Study Length: 7 months

Study Requirements
  • Individuals age 50 or older with mild–moderate Alzheimer's disease
  • Not currently taking memantine
  • Stable treatment with donepezil
  • A study partner who will accompany the participant to all clinic visits
MaryAnn Oakley at 412-692-2721 or oakleym@upmc.edu


Description: The purpose of this study is to determine whether short-term followed by long-term, low-volume plasma exchange (a process of blood filtering) is able to modify Alzheimer Disease patient's cognitive, functional, and behavioral symptoms.

Study Length: 14 months (Six weekly plasmapheresis sessions followed by 12 monthly plasmapheresis sessions)

Study Requirements
  • 55-85 years of age
  • Individuals with a diagnosis of mild to moderate Alzheimer's disease
  • A study partner who will accompany the participant to all clinic visits
Donna Simpson, 412-692-2717 or simpsondm@upmc.edu or
MaryAnn Oakley at 412-692-2721 or oakleym@upmc.edu

The University of Pittsburgh Alzheimer’s Disease Research Center (ADRC) is looking for volunteers with or without mild memory loss to participate in our research.
You may qualify if:
  • You are 65 years or older with no memory complaints or,
  • You have a memory complaint and think you might have mild memory loss,


  • You have a “study partner" who can accompany you to clinic visits. A study partner is a family member or close friend who knows you well and can answer questions about your memory and functioning.
Please call the ADRC at 412-692-2700 for more information or to inquire about how you can volunteer for research to help fight Alzheimer’s disease or complete a memory evaluation application and return it to us.

Other studies we are recruiting for »