The ADRC is currently recruiting participants for:

    Biogen (Emerge-Engage) Study

    Description: This study will evaluate the efficacy and safety of an investigational drug, Aducanumab, for individuals with Early, Mild Alzheimer's Disease or certain types of Mild Cognitive Impairment (MCI). Study medication is administered by a once monthly infusion.

    Study Length: 18 months

    Study Requirements
    • 50-85 years of age
    • Diagnosis of mild Alzheimer's disease or certain types of MCI
    • A study partner who will accompany the participant to all clinic visits
    Contact:
    Carolyn Rickard at 412-692-2707 or mishlercj@upmc.edu or
    MaryAnn Oakley at 412-692-2721 or oakleym@upmc.edu
    A4 Study

    Description: The Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease Trial, or A4 Study, is among a new generation of clinical trials being developed to test therapies that might prevent, or at least delay the onset of, Alzheimer's disease in cognitively normal people who may be at risk as evidenced by a PET scan.

    Study Length: 3 years

    Study Requirements
    • 65 to 85 years of age
    • Normal thinking and memory abilities
    • Have a study partner with whom you have contact at least once a week who can answer questions about you once a year (contact may be in person or by phone)
    • Willing and able to receive IV infusions of the investigational drug (solanezumab) or a placebo every 4 weeks for 3 years
    Contact:
    MaryAnn Oakley at 412-692-2721 or oakleym@upmc.edu or
    Katy Zorich at 412-692-2719 or orchowskik3@upmc.edu
    Connectomes in Brain Aging

    Description: This study will determine how different parts of the brain are connected and how these connections allow people to think, behave and feel. The study will involve 2-3 days of scanning and tests. Some people will be asked to return after two years.

    Study Length: 2-3 days and for some two years

    Study Requirements
    • 50-89 years of age
    • Cognitively normal; or have Mild Cognitive Impairment (MCI); or have been diagnosed with Alzheimer's disease.
    Contact:
    MaryAnn Oakley at 412-692-2721 or oakleym@upmc.edu or
    Rebecca Roush 412-586-9860


The University of Pittsburgh Alzheimer Disease Research Center (ADRC) is one of the nation's leading research centers specializing in the diagnosis of Alzheimer's disease and related disorders. Through outpatient evaluations, participants and their families receive state-of-the-art diagnostic assessments and contribute to the scientific study of Alzheimer's disease

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Our memory evaluation is an extensive diagnostic evaluation of individuals with suspected Alzheimer's disease and other types of memory loss and/or cognitive impairment. The professionals at the ADRC understand that this is a stressful process for all and assure that individuals will be treated with sensitivity and respect.

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