The University of Pittsburgh Alzheimer Disease Research Center (ADRC) is one of the nation's leading research centers specializing in the diagnosis of Alzheimer's disease and related disorders. Through outpatient evaluations, participants and their families receive state-of-the-art diagnostic assessments and contribute to the scientific study of Alzheimer's disease

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Our memory evaluation is an extensive diagnostic evaluation of individuals with suspected Alzheimer's disease and other types of memory loss and/or cognitive impairment. The professionals at the ADRC understand that this is a stressful process for all and assure that individuals will be treated with sensitivity and respect.

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The ADRC is currently recruiting participants
for these clinical trials:

    Dementia with Lewy Bodies Consortium

    Description: The purpose of this study is to collect clinical information, brain imaging scans, and biological samples from people that have dementia with Lewy bodies. This information will help researchers improve the diagnosis, care, and treatment of patients with this disease.

    Study Length: 5 years

    Study Requirements
    • Age 40-90
    • Diagnosis of Lewy Body Dementia (DLB) or high likelihood
    • A study partner who will accompany you to all study visits
    Contact:
    Donna Simpson at 412-692-2717 or simpsondm@upmc.edu or MaryAnn Oakley at 412-692-2721 or oakleym@upmc.edu
    Alzheimer's Disease Neuroimaging Initiative - 3 (ADNI3)

    Description: The overall goal is to determine the relationships among the clinical, cognitive, imaging, genetic and biochemical biomarker characteristics of the entire spectrum of Alzheimer's disease (AD) from its earliest stages. Subjects will undergo longitudinal clinical and cognitive assessments, computerized cognitive batteries, biomarker and genetic tests, PET (FDG, amyloid and tau) and MRI scans and cerebral spinal fluid (CSF) collection. For more information about the ADNI3 study visit http://www.adni-info.org/

    Study Length: up to 5 years

    Study Requirements
    • 55-90 years of age
    • Cognitively normal; or have Mild Cognitive Impairment (MCI); or have been diagnosed with Alzheimer’s disease
    • A study partner who will accompany you to all study visits
    Contact:
    MaryAnn Oakley at 412-692-2721 or oakleym@upmc.edu
    LATTICE

    Description: The purpose of this study is to examine the potential disease modifying properties of lithium in individuals with mild cognitive impairment (MCI). For additional information visit: youtu.be/vcNBr6QSp4w

    Study Length: 2 years

    Study Requirements
    • Age 60 years or older
    • Diagnosis mild cognitive impairment
    Contact:
    MaryAnn Oakley at 412-692-2721 or oakleym@upmc.edu
    Connectomes in Brain Aging

    Description: This study will determine how different parts of the brain are connected and how these connections allow people to think, behave and feel. The study will involve 2-3 days of scanning and tests. Some people will be asked to return after two years.

    Study Length: 2-3 days and for some two years

    Study Requirements
    • 50-89 years of age
    • Cognitively normal; or have Mild Cognitive Impairment (MCI); or have been diagnosed with Alzheimer's disease.
    Contact:
    MaryAnn Oakley at 412-692-2721 or oakleym@upmc.edu or
    Rebecca Roush 412-586-9860


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